Detroit Lions wide receiver Kalif Raymond (ankle) has been ruled out ahead of the Week 13 matchup against the Green Bay Packers. Raymond made an early exit during Sunday's win over the New York Giants. Sadly, the 31-year-old won't have enough time to get ready before this Thanksgiving matchup. His absence should mean Isaac TeSlaa (hand) takes over as the No. 3 wideout, assuming he's cleared to play. Otherwise, Dominic Lovett might get a look. Neither are viable fantasy options heading into this game.

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Miami Dolphins wide receiver Jaylen Waddle (foot) was a limited participant during Wednesday's practice session. This seems a bit odd as Waddle wasn't dealing with a foot injury before the bye week. It's unclear when he suffered the injury, but the fact he was limited suggests it's a minor issue. Waddle should be ready to go against the New Orleans Saints in Week 13. Fantasy managers should check back on Thursday and Friday just in case something changes.

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Baltimore Ravens running back Keaton Mitchell is set to see a bit more action in Week 13 after Justice Hill (neck) has officially been ruled out. In Week 12, Mitchell finished with more touches (3) than Hill (0) despite the fact that he had a 19% snap share compared to Hill's 25%. The young speedster has been more efficient and explosive with his touches this season, and more action against a vulnerable defense should mean great opportunities. The Cincinnati Bengals rank last against opposing backfields and have given up a total of nine touchdowns on the ground and five through the air to running backs. While this all equates to good things for Mitchell, he's still projected outside the top 50 and would be a very risky flex option, even in deeper leagues.

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Miami Dolphins tight end Darren Waller (pectoral) had his 21-day practice window opened this week. On Wednesday, Waller practiced for the first time since suffering a pectoral injury in Week 7. The 33-year-old was a limited participant, which isn't shocking given how long he has been sidelined. It's possible that Waller does return this weekend to take on the New Orleans Saints. However, fantasy managers shouldn't be shocked if Waller needs more time to get ready. Fantasy managers will need to check back after practice on Thursday and Friday. If he remains out, Greg Dulcich figures to remain the top tight end for another week.

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New Orleans Saints running back Devin Neal (ankle) was a limited participant during Wednesday's practice session. Neal took over as the lead back for the final three quarters after Alvin Kamara (knee) exited early during Sunday's game. Neal looks like he picked up a minor ankle injury along the way. The fact he was limited suggests that Neal is on track to play against the Miami Dolphins in Week 13. He rushed the ball seven times for 18 yards, while hauling in five receptions for 43 yards in the loss. Kamara is trending in the wrong direction right now, so Neal could take over as the lead back this weekend.

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Baltimore Ravens running back Derrick Henry has finished as an RB1 in each of the last two weeks, and has registered double-digit fantasy points over his last six consecutive games in half-PPR formats. Despite an ugly average of 3.0 yards per carry last week, he's always a threat to score, like he did twice against the New York Jets. Their Week 13 matchup against the Cincinnatti Bengals should mean a huge green light for Henry. They're ranked 32nd against opposing backfields and have allowed an average of 32.18 fantasy points per game. Henry is projected as a mid-level RB1 this week and should remain in starting lineups regardless of format.

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New Orleans Saints running back Alvin Kamara (knee, ankle) was a non-participant during Wednesday's practice session. Kamara was forced to exit early during Sunday's loss to the Atlanta Falcons. He underwent an MRI, which revealed that Kamara is dealing with a sprain. There are still two more days for Kamara to get healthy enough to play, but fantasy managers should prepare to be without him. If he sits, Devin Neal figures to take over as the lead back for the Week 13 matchup against the Miami Dolphins. Neal could offer RB2 value if he takes over the starting gig this weekend.

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New Orleans Saints wide receiver Chris Olave (back) was forced to make an early exit from Wednesday's practice session. It sounds like Olave is dealing with a minor back issue, so the team pulled him out of drills as a precaution. Fantasy managers should consider Olave as day-to-day. He figures to be ready to go for Sunday's game against the Miami Dolphins. Fantasy managers should monitor the injury report over the next two days. If active, fantasy managers should be able to trust Olave as a WR2 for Week 13.

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Baltimore Ravens quarterback Lamar Jackson has registered a rough stretch of fantasy finishes over the last three games as he continues to deal with a slew of injuries. This week, he was dealing with a toe issue that kept him out of the walkthrough on Monday, but he was a full participant the rest of the way. His upside remains one of the highest in the league, especially against a Cincinnati Bengals defense that has allowed the third most fantasy points to quarterbacks this season, and the second most over the last four weeks. A lot of these matchups with the Bengals have ended up in a shootout, and Jackson's 10-2 against them in his career with a total of 2,472 yards, 22 touchdowns, and four interceptions. For that reason, he's still projected as a QB1, but he's become a bit more worrisome week by week.

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San Francisco 49ers kicker Eddy Pineiro (hamstring) was a non-participant during Wednesday's practice session. Pineiro wasn't able to practice at all last week before eventually getting ruled out for the Week 12 matchup against the Carolina Panthers. It's not looking good as Pineiro is sidelined to begin this week as well. He's currently considered week-to-week due to a Grade 1 hamstring strain. In his absence, Matt Gay was perfect on all four of his kick attempts. Gay figures to get another start if Pineiro is sidelined versus the Cleveland Browns in Week 13.

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Seattle Seahawks running back Kenneth Walker III (glute) is on the team's Week 13 injury report and was listed as limited in Wednesday's practice with a glute injury, according to Michael-Shawn Dugar of The Athletic. Walker, who has a history of lower-body injuries, is worth monitoring ahead of a Week 13 clash against the Minnesota Vikings this weekend. The 25-year-old continues to share playing time with backfield mate Zach Charbonnet, but he has been much more efficient with his opportunities in 2025, compiling 677 rushing yards and four touchdowns on his 147 rushing attempts. Walker has also added 157 receiving yards. If Walker is able to play against Minnesota, he should be viewed as a low-end RB2 for fantasy managers. He played through his glute injury in last week's win over the Titans and had 14 touches for 101 scrimmage yards.

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Las Vegas Raiders tight end Michael Mayer (ankle) was a non-participant in the team's first practice of the week on Wednesday due to an ankle issue, according to Ryan McFadden of ESPN. Mayer only played 13 offensive snaps in Sunday's loss to the Cleveland Browns before injuring his ankle and never returning. The 24-year-old's status is now up in the air for this weekend's divisional rematch against the Los Angeles Chargers. Mayer has not been a realistic TE2 fantasy football streamer this year as long as Brock Bowers has been healthy. In nine total games, the former second-rounder in 2023 out of Notre Dame has 22 catches for 182 yards and only one touchdown on 32 targets. If Mayer is unavailable to play against L.A. on Sunday, it should open up more playing time for rookies Dont'e Thornton Jr. and Jack Bech in three-wide sets.

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Las Vegas Raiders rookie first-round running back Ashton Jeanty (ankle) is not listed on the team's Week 13 injury report, according to Ryan McFadden of ESPN. Jeanty injured his ankle late in Sunday's loss to the Cleveland Browns, but it was nothing serious, and he'll be ready to play for a Week 13 date with the division-rival Los Angeles Chargers. The 21-year-old from Boise State didn't find much room to run on the ground in Week 12 (17 carries for 50 yards), but he salvaged his fantasy day with a season-high eight receptions for 58 yards and a touchdown through the air. Jeanty has struggled to put up numbers on the ground in his first NFL season behind a bad offensive line, and things probably won't get any easier this weekend. But the volume alone will make Jeanty a low-end RB1/high-end RB2 in fantasy football. He had 11 carries for 43 yards and three catches for one yard in the previous meeting with the Chargers back on Sept. 15.

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Las Vegas Raiders wide receiver Tre Tucker (knee) was listed as limited in Wednesday's practice with a knee injury, according to ESPN's Ryan McFadden. Tucker didn't show any signs of an injury in the Week 12 loss to the Cleveland Browns on Sunday, playing 95% of the offensive snaps and finishing with three catches on a team-high 10 targets for 28 yards. The 24-year-old may need to upgrade to a full practice this week to avoid a questionable tag for Week 13 against the division-rival Los Angeles Chargers, though. Tucker has seen more looks in the last two games, hauling in seven of 18 targets for 75 yards and a touchdown. Veteran Tyler Lockett has plenty of chemistry with quarterback Geno Smith, though, and tight end Brock Bowers also takes away valuable looks. In what has been a bad Raiders offense in 2025, Tucker has limited fantasy upside as a WR4/flex heading into a rematch against L.A. Tucker had just three catches on eight targets for a season-low 12 yards in the first game against the Chargers.

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Los Angeles Chargers rookie first-round running back Omarion Hampton (ankle) said he was dealing with a fractured ankle, according to Daniel Popper of The Athletic. Hampton also said he feels "amazing" and is hoping to be a full-go once he's activated from Injured Reserve. The 22-year-old Ohio State product fractured his ankle in Week 5 and has been out since, but he returned to a limited practice on Wednesday and has a shot to play this Sunday versus the division-rival Las Vegas Raiders. Offensive coordinator Greg Roman hinted this week that Hampton could be in a timeshare with Kimani Vidal upon his return, which somewhat clouds his fantasy value upon his return. Hampton showed just before his ankle fracture that he's capable of RB1 upside with a heavy workload, but fantasy managers may want to temper expectations initially if L.A. looks to ease him back into the fold.

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Denver Broncos head coach Sean Payton isn't ruling out a potential return from running back J.K. Dobbins (foot) later in the year, according to Parker Gabriel of The Denver Post. Dobbins was previously ruled out for the rest of the season due to a foot injury, but if the Broncos make a deep postseason run, Dobbins might be able to return. For fantasy football purposes, managers in single-year leagues can dump Dobbins to the waiver wire if they haven't already done so, since he won't be able to help them before the end of the year. Denver will move forward with rookie second-rounder RJ Harvey as their primary backfield option with Dobbins out, but Jaleel McLaughlin and Tyler Badie will also be involved in change-of-pace roles. Harvey will have RB2 upside the rest of the way, while McLaughlin and Badie are simply bench stashes in deeper fantasy leagues.

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Tennessee Titans tight end Chig Okonkwo (foot) finds himself on the injury report yet again in Week 13, and he was listed as a limited practice participant on Wednesday, according to ESPN's Michael DiRocco. Okonkwo shouldn't have any problem playing through his foot injury this weekend against the division-rival Jacksonville Jaguars unless he suffers a setback in practice on Thursday or Friday. The 26-year-old is still looking for his first touchdown of the 2025 season and has not had much fantasy upside in one of the worst offenses in football while sharing targets with rookie TE Gunnar Helm. Okonkwo has gone over 50 receiving yards in a game this year just three times in 11 games, although two of those instances have come in the last four games. Okonkwo will have less appeal as a TE2 streamer in fantasy football in Week 13 if rookie receiver Elic Ayomanor (hamstring) is able to return.

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Tennessee Titans rookie wide receiver Elic Ayomanor (hamstring) was listed as limited in the team's practice on Wednesday as he continues to battle through a hamstring injury, according to Michael DiRocco of ESPN. While it's unknown if Ayomanor will be able to return in a Week 13 divisional matchup against the Jacksonville Jaguars this Sunday, he's on the right track with a limited practice on Wednesday. The 22-year-old pass-catcher was unable to play in the Week 12 loss to the Seattle Seahawks, which allowed fellow rookie Chimere Dike to work as Tennessee's WR1. Remember, veteran Calvin Ridley (leg) is out for the year with a broken fibula. If the fourth-round rookie gets cleared to return this weekend, he'll be in play as a WR4/flex in deeper fantasy football leagues. Through his first 10 NFL games, Ayomanor has 28 receptions on 59 targets for 334 yards and two touchdowns.

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Washington Commanders running back Chris Rodriguez Jr. (illness) missed Wednesday's practice due to an illness, according to The Washington Post's Nicki Jhabvala. Rodriguez's status for the Sunday night primetime game against the visiting Denver Broncos in Week 13 is worth monitoring, but the 25-year-old should be cleared by then. In recent weeks, C-Rod has taken over early-down duties in Washington's backfield from struggling rookie Jacory Croskey-Merritt, while Jeremy McNichols continues to be the team's primary pass-catching back. Rodriguez should be good to go against Denver, but his fantasy stock is trending down this week in a bad matchup with backup quarterback Marcus Mariota set to make another start. The Broncos' strong defense has allowed the third-fewest rushing yards per game (88.5) in 2025.

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Washington Commanders quarterback Jayden Daniels (elbow) was listed as limited in the team's first practice of the week on Wednesday, according to Nicki Jhabvala of The Washington Post. Daniels will most likely be officially ruled out for Week 13 against the Denver Broncos on Sunday Night Football, but there's a chance he'll return in Week 14 against the Minnesota Vikings if he continues to make progress. The 24-year-old second-year signal-caller has not played since suffering a gruesome dislocated left (non-throwing) elbow in the Week 9 loss to the Seattle Seahawks. Even though the Commanders have lost six straight games to put them well out of playoff contention, it sounds as though Daniels will return when he's cleared in December. The former second overall pick also missed a few games early in the season with a knee injury. In his six games, Daniels has thrown for 1,184 yards, eight touchdowns, and two interceptions.

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