Rookie J.C. Escarra hit a pinch-hit walk-off sacrifice fly in the 10th inning Wednesday night as the New York Yankees earned a 4-3 victory over the visiting San Diego Padres after being no-hit for 6 1/3 innings by Dylan Cease.

Cody Bellinger homered to end Cease's bid for his second no-hitter and the third in San Diego history. Former Padre Trent Grisham then hit a pinch-hit two-run homer off Jason Adam in the eighth to tie the game.

After Oswaldo Cabrera sacrificed automatic runner Jasson Dominguez to third, Escarra batted for Oswald Peraza. He fouled off two pitches before driving a 2-2 pitch off Jeremiah Estrada (1-2) to the warning track in left field to easily score Dominguez. Escarra's RBI gave the Yankees a second straight win after blowing a three-run lead in the eighth inning Monday.

Cease had a no-hitter going until Bellinger's home run. Cease struck out nine and walked two in 6 2/3 innings before appearing to get hurt during an at-bat against Dominguez. Cease exited with a right forearm cramp.

Guardians 8, Nationals 6

Carlos Santana ripped a three-run double to trigger an eight-run sixth inning as Cleveland rallied to beat host Washington and take two out of three in the series.

Gabriel Arias had four hits and Angel Martinez contributed the go-ahead two-run single in the sixth. Guardians starter Logan Allen gave up three runs and seven hits in four-plus innings. Joey Cantillo (1-0) threw a scoreless fifth and Emmanuel Clase tossed a scoreless ninth for his eighth save.

Amed Rosario had three hits and two RBIs while CJ Abrams and James Wood added three hits apiece for the Nationals, who left 15 runners on base. Mike Soroka (0-2) came off the injured list and fanned eight over five scoreless innings before allowing four runs without getting an out in the sixth.

Cardinals 5, Pirates 0

Sonny Gray pitched seven shutout innings and allowed just two hits to lead host St. Louis to the shutout and the three-game sweep of Pittsburgh.

Gray (4-1) struck out eight and walked one while combining with Kyle Leahy and Chris Roycroft for St. Louis' fourth shutout of the season. Masyn Winn delivered a pair of RBI doubles while Lars Nootbaar contributed three hits for the Cardinals, who won their season-high fifth in a row.

Pittsburgh's Mitch Keller (1-4) went six innings and allowed three runs on seven hits. The Pirates lost their season-high seventh straight game and were shut out for the seventh time.

Astros 9, Brewers 1

Framber Valdez threw seven quality innings and Jeremy Pena homered and drove in four as Houston salvaged the finale of a three-game series at Milwaukee.

Valdez (2-4) allowed one run on three hits. Yainer Diaz delivered a two-run double for the Astros, who stacked up eight hits and seven walks.

Brewers starter Quinn Priester (1-1) surrendered three runs (one earned) on three hits in his five-inning stint. Eric Haase's 425-foot solo homer in the fifth accounted for the Brewers' scoring as their three-game winning streak came to a close.

Giants 3, Cubs 1

Robbie Ray and three relievers scattered four hits and Wilmer Flores went 3-for-4 with an RBI and a run in San Francisco's victory over host Chicago.

Ray (5-0) allowed a run and three hits in six innings as the Giants took two of three games in the series. San Francisco improved to 8-0 in his starts this season.

Cubs starter Ben Brown (3-3) gave up three runs in his five innings but struck out nine batters. Chicago scored their lone run on Pete Crow-Armstrong's wind-aided RBI double in the bottom of the fourth inning.

Twins 5, Orioles 2

Byron Buxton went 2-for-4 with a three-run homer, and Minnesota posted a win over Baltimore in Minneapolis.

Harrison Bader added a pinch-hit, two-run shot for the Twins, who won their fourth game in a row. Reliever Danny Coulombe (1-0) threw one scoreless inning, and Jhoan Duran struck out the side in the ninth for his fifth save.

Ramon Laureano went 2-for-4 with a double and a solo home run for the Orioles, who have lost four consecutive games. Charlie Morton (0-7) gave up three runs on four hits in four innings.

Mets 7, Diamondbacks 1

Juan Soto collected two solo home runs and three RBIs and Kodai Senga pitched six shutout innings as New York beat host Arizona to take the rubber game of a three-game series.

Soto's 427-foot homer to center field off Merrill Kelly (3-2) broke a scoreless tie in the sixth, and his opposite-field homer made it 4-0 in the eighth. It was his second two-homer game of the season. Senga (4-2) held an opponent scoreless for the fourth time in seven starts this season and lowered his ERA to 1.16.

Corbin Carroll had two hits, including an eighth-inning homer, and Alek Thomas doubled and singled for the Diamondbacks, who have lost four of six.

Mariners 6, Athletics 5

Dylan Moore's two-out double in the eighth inning plated the go-ahead run for Seattle, who rallied from an early 5-0 deficit to beat the host Athletics.

Rowdy Tellez added a three-run homer to bring the Mariners to within 5-4 in the sixth inning. Eduard Bazardo (1-0) pitched 1 1/3 innings in relief to earn the win, while Andres Munoz picked up his 13th save.

Jacob Wilson went 4-for-5 with two doubles, a run scored and an RBI for the Athletics, while Lawrence Butler smacked his sixth homer. Noah Murdock (1-1) allowed the tying and go-ahead runs in the eighth and absorbed the loss.

Dodgers 10, Marlins 1

Los Angeles broke up a low-scoring game by plating six runs in the seventh inning and cruised past host Miami.

Freddie Freeman singled twice and served a bases-clearing triple into right-center field to give the Dodgers a 6-0 cushion. Landon Knack (2-0) hurled five scoreless innings and Matt Sauer completed the final four frames to earn his first career save.

Cade Gibson (0-1) allowed two runs in just his second major league outing. Starter Valente Bellozo held the reigning World Series champions to just one hit in 5 1/3 innings.

Phillies 7, Rays 0

Cristopher Sanchez allowed one hit over six scoreless innings and Taijuan Walker struck out seven over the final three frames, fueling visiting Philadelphia to a victory over Tampa Bay.

Sanchez (4-1) fanned five and walked three. Walker struck out the side in both the seventh and eighth innings and fanned Curtis Mead to end the game in the ninth, earning the first save of his career.

Philadelphia's Trea Turner homered and drove in two runs and Bryce Harper ripped a two-run double as part of a five-run fourth. Bryson Stott added a pair of RBI singles. Tampa Bay starter Shane Baz (3-2) permitted six runs on eight hits in 3 1/3 innings.

Reds 4, Braves 3

TJ Friedl hit a pair of home runs to help visiting Cincinnati end a four-game losing streak with a win over Atlanta.

Friedl began the game with a home run and added another solo shot in the third inning. The Reds lost ace Hunter Greene, who left the game with a groin injury while warming up to start the fourth. The right-hander looked strong over three scoreless innings as allowed two hits.

Brent Suter (1-0) replaced Greene and allowed one run over two innings. Emilio Pagan struck out two and earned his ninth save. Atlanta's Grant Holmes (2-3) pitched 5 1/3 innings and allowed four runs on seven hits. Drake Baldwin hit a solo shot for the Braves, who had won three straight.

Royals 2, White Sox 1

Michael Wacha allowed three hits over seven scoreless innings and Bobby Witt Jr. clubbed a two-run homer as host Kansas City hung on to beat Chicago.

Witt's long ball was just enough to give the Royals their fifth straight win and 14th in the last 16 games. Kansas City has also won each of its past 10 home meetings with Chicago. Wacha (2-4) struck out five while extending his home shutout streak against the White Sox to 21 innings.

Royals closer Carlos Estevez made things interesting in the ninth, allowing Miguel Vargas' second double of the game then back-to-back singles to Luis Robert Jr. -- making it a one-run contest -- and Matt Thaiss. But he fanned Andrew Vaughn, got Brooks Baldwin to ground into a fielder's choice and struck out Josh Rojas to register his 11th save.

Red Sox 6, Rangers 4

Wilyer Abreu and Alex Bregman both went 3-for-4 with three RBIs to lead Boston over visiting Texas.

Abreu homered twice and hit an RBI double in his last three at-bats as the Red Sox overcame a 3-2 deficit. Brennan Bernardino (2-1) earned the win in relief by pitching a perfect seventh inning and Aroldis Chapman picked up his fifth save. Bregman hit his 200th career homer in the fourth inning.

Josh Jung and Adolis Garcia both homered for Texas. Reliever Jacob Webb (2-2) took the loss.