Joey Bart's walk-off single with the bases loaded in the 13th inning lifted the host Pittsburgh Pirates to a 2-1 win over the St. Louis Cardinals.

Bart's deep fly ball off reliever Chris Roycroft (0-2) landed just out of the reach of left fielder Lars Nootbaar and allowed Alexander Canario to score easily. The Pirates took two of three from their National League Central division rivals and won despite being no-hit for 6 2/3 innings and one-hit for 8 2/3.

Cardinals starter Erick Fedde was pulled after six no-hit innings and 88 pitches. Pirates starter Mitch Keller allowed four hits over 7 1/3 scoreless innings.

Jordan Walker's RBI single in the top of the 12th off Justin Lawrence (1-0) gave the Cardinals a 1-0 lead. The Pirates answered, however, in the bottom half when Tommy Pham singled to score Ke'Bryan Hayes ahead of Bart's hit.

Giants 8, Reds 6 (10 innings)

Mike Yastrzemski launched a two-run homer with one out in the bottom of the 10th inning, allowing San Francisco to walk off visiting Cincinnati for a victory and avoid a three-game sweep.

Yastrzemski's shot off Emilio Pagan (0-1) went over the right field wall. Giants starter Justin Verlander was pulled after 5 2/3 innings, charged with six runs (five earned). He struck out nine.

Nick Martinez lasted just 5 2/3 innings for the Reds, during which he allowed four runs. He fanned eight.

Brewers 17, Rockies 2

Jackson Chourio homered, doubled and drove in five runs, William Contreras and Christian Yelich each went deep for the second straight game, and Milwaukee routed Colorado in Denver.

Garrett Mitchell, Joey Ortiz, Brice Turang, Yelich and Chourio had two hits apiece for the Brewers, and Grant Anderson (1-0) got the win with two scoreless innings of relief. Milwaukee has won three straight games.

Ryan McMahon homered and Ezequiel Tovar and Kris Bryant had two hits apiece for the Rockies. Antonio Senzatela (0-2) allowed nine runs, eight earned, in 4 1/3 innings.

Twins 4, Royals 0

Joe Ryan continued his mastery of Kansas City hitters by tossing two-hit ball over seven scoreless innings, getting the win for visiting Minnesota.

Ryan (1-1) struck out four and walked none while improving to 7-0 with a 1.30 ERA in nine career starts against the Royals. Griffin Jax replaced Ryan and gave up one hit during a scoreless eighth inning. Jhoan Duran worked around a walk in the ninth to complete the three-hitter.

Ty France went 3-for-4 with a homer and two RBIs, and Matt Wallner also went deep for the Twins. Edouard Julien contributed an RBI single as Minnesota ended a three-game losing streak.

Mariners 7, Astros 6

Randy Arozarena hit a grand slam in the eighth inning and drew a bases-loaded walk in the ninth to drive in the winning run as host Seattle defeated Houston.

Seattle trailed 5-0 before Arozarena's slam, and Julio Rodriguez added a two-run double in the ninth to even the score at 6. Trailing 6-4 entering the bottom of the ninth, the Mariners got to Astros reliever Bryan Abreu (0-1) after closer Josh Hader had worked in two of the previous three days. Mariners reliever Casey Lawrence (1-0) got the victory.

Jose Altuve, Isaac Paredes, Jeremy Pena and Cam Smith had two hits apiece for the Astros. Pena scored twice and stole a base.

Yankees 4, Tigers 3

Ben Rice hit a two-run homer, Max Fried struck out 11 and New York salvaged the finale of a three-game series in Detroit.

Fried (2-0) allowed five hits and didn't issue a walk in seven scoreless innings. Mark Leiter Jr. recorded the save after the Tigers staged a three-run rally in the ninth against Devin Williams. Aaron Judge added a two-run single.

Zach McKinstry had two hits and two RBIs for the Tigers. Reliever Tyler Holton (1-1) took the loss.

Guardians 3, White Sox 2

Jhonkensy Noel delivered an RBI single for one of his two hits, Carlos Santana homered and Cleveland cut down Chicago's Mike Tauchman, who pulled up with an injury before reaching home plate, for the final out of its victory.

Noel's two hits and Santana's homer were the only three hits for the Guardians, who have totaled four runs and six hits in winning the first two games of the three-game set. Paul Sewald (1-1) won in relief, and Emmanuel Clase got his first save despite allowing a run in the ninth.

Tauchman collected three hits, Miguel Vargas had two hits and Lenyn Sosa added an RBI single for the White Sox, who have lost seven straight. Sean Burke (1-2) gave up three runs in three innings.

Rays 5, Angels 4

Jose Caballero's first-inning grand slam and Yandy Diaz's seventh-inning solo homer provided all the offense host Tampa Bay would need in a victory over Los Angeles.

Caballero hit his slam off Angels starter Yusei Kikuchi (0-2). Rays starter Ryan Pepiot (1-1) gave up three homers but got the victory after going five innings and six hits and three runs.

The Angels hit four homers, all solo shots, two by Kyren Paris and one apiece from Taylor Ward and Jorge Soler Paris has a club-best five long balls, and he is hitting .440 (11-for-25).

Padres 2, Athletics 1

Randy Vasquez threw five quality innings and Xander Bogaerts went 3-for-5 and scored twice as San Diego got the victory over the A's in West Sacramento, Calif.

Vasquez (1-1) allowed just one run on one hit while striking out a batter and walking three. Oscar Gonzalez tallied a pair of hits, including an RBI single, while Manny Machado and Jason Heyward also recorded two-hit performances as San Diego took two of three against the Athletics.

Osvaldo Bido (1-1) went five innings, giving up two runs on nine hits for the A's. Brent Rooker and Jacob Wilson were responsible for the Athletics' only two hits.

Diamondbacks 9, Orioles 0

Corbin Carroll, Pavin Smith, Josh Naylor and Geraldo Perdomo homered and Brandon Pfaadt pitched six scoreless innings as Arizona shut out Baltimore in Phoenix.

Carroll, Perdomo, Smith and Naylor -- the top four in the Arizona lineup -- were 11-for-17 with four homers, seven RBIs and seven runs. Naylor had three hits and three RBIs, Smith had three hits and two RBIs and Perdomo had three hits. Pfaadt (2-1) helped the Diamondbacks win their second straight after a three-game losing streak.

Dean Kremer (1-2) gave up eight hits and six runs in 4 2/3 innings as the Orioles lost for the sixth time in eight games.

Dodgers 6, Nationals 5

Teoscar Hernandez and Andy Pages homered and visiting Los Angeles rallied past Washington to salvage the finale of the three-game series.

Hernandez had two hits and drove in three runs for Los Angeles, while Shohei Ohtani and Tommy Edman each had two hits. Blake Treinen worked the ninth for his second save.

CJ Abrams homered for Washington, which had won four straight after losing six of seven.

Blue Jays 2, Red Sox 1 (11 innings)

Bo Bichette hit a go-ahead sacrifice fly in the top of the 11th before Nick Sandlin pitched a 1-2-3 inning in the bottom of the frame, lifting Toronto to a win over Boston.

Vladimir Guerrero Jr. (3-for-5) and Andres Gimenez (2-for-3) logged five of the Blue Jays' six hits. Toronto starter Kevin Gausman struck out 10 and allowed just one unearned run in eight innings. Jeff Hoffman (1-0) got the win, and Nick Sandlin registered his first save of the season.

Red Sox batters struck out 14 times, but Rafael Devers (2-for-5, two doubles) was a major contributor. Tanner Houck delivered 6 2/3 innings of one-run ball.

Phillies 4, Braves 3

Trea Turner launched a go-ahead solo home run in the top of the ninth inning, leading Philadelphia to a win over host Atlanta.

Turner finished 2-for-4 and Bryce Harper connected on a two-run homer in the seventh inning for the Phillies. Starter Taijuan Walker threw 4 2/3 shutout innings as Philadelphia leveled the three-game series at one win apiece.

Austin Riley went 2-for-5 with a solo homer for the Braves, while Marcell Ozuna, Orlando Arcia and Bryan De La Cruz each finished with two hits. Grant Holmes pitched four-plus scoreless innings for the Braves.

Marlins 5, Mets 0

Max Meyer combined with two relievers on a two-hitter and Matt Mervis hit a two-run homer and drove in three runs as Miami won at New York.

Meyer (1-1) pitched 6 1/3 innings. Anthony Bender tossed 1 2/3 innings, and Lake Bachar handled the ninth as the Marlins captured the series finale after dropping the first two.

New York's Tylor Megill (2-1) allowed two unearned runs on six hits in four-plus innings. The Mets saw a six-game winning streak end and took their first home loss.

Rangers 6, Cubs 2

Corey Seager hit two home runs, Jonah Heim added a two-run blast and Tyler Mahle was sterling on the mound as visiting Texas defeated Chicago to salvage the finale of a three-game series.

Mahle (2-0) allowed one run on two hits over seven innings. The Rangers got two hits each from Seager, Heim and Leody Tavares.

Chicago starter Shota Imanaga (2-1) went seven innings, surrendering five runs on seven hits. Seiya Suzuki had two hits, including an RBI single.