Houston Rockets center Steven Adams (calf) is questionable for Friday's matchup with San Antonio in Austin, per the Houston Chronicle's Varun Shankar. The 33-year-old missed Wednesday's opener after developing right calf tightness following a practice earlier in the week. Houston also plans to sit Adams for one leg of back-to-backs early in the season, with another game Saturday in Atlanta. He averaged 8.6 rebounds in 22.8 minutes last season. If Adams remains out, Clint Capela should continue backing up Alperen Sengun, though Capela logged only eight minutes in the opener.

Houston Rockets guard Reed Sheppard (knee) is questionable for Friday's matchup with San Antonio due to a left knee contusion and bone bruise, per the Houston Chronicle's Varun Shankar. The 22-year-old is coming off a quiet opener against Dallas, scoring three points on 1-for-6 shooting from deep with three turnovers in 16 minutes. Marcus Smart played 26 minutes off the bench, while Fred VanVleet's return has tightened Houston's backcourt rotation. If Sheppard sits, Smart and Bogdan Bogdanovic could see additional work. Sheppard averaged 13.5 points, 2.8 threes and 1.5 steals last season.

San Antonio Spurs forward Keldon Johnson (mouth) is questionable for Friday's game against Houston in Austin, per Matt Guzman. The reigning Sixth Man of the Year needed three stitches for a deep cut inside his right cheek after Tuesday's 116-104 loss to Oklahoma City but still finished with 10 points, four rebounds, one assist, and two steals in 20 minutes. With Tobias Harris (calf) also out, Julian Champagnie could take on a larger wing role if Johnson sits, while Harrison Barnes and Carter Bryant may also pick up minutes.

San Antonio Spurs guard De'Aaron Fox (wrist) is questionable for Friday's matchup with Houston due to a right wrist sprain. The two-time All-Star played 32 minutes in Tuesday's season opener, finishing with 14 points, seven rebounds, seven assists, and one steal on 6-for-9 shooting. San Antonio visits Dallas on Saturday to complete a back-to-back, giving the Spurs another reason to be cautious with Fox. If he sits Friday, Dylan Harper and Stephon Castle should take on more playmaking responsibility, while Julian Champagnie could move into the starting five.

Dallas Mavericks forward Santi Aldama (knee) has been ruled out for Friday's road game against Indiana, per Dallas Sports Journal's Grant Afseth. It will be his second straight absence to open the season as he works back from right knee surgery, though head coach Dusty May said earlier this week that Aldama was "getting very close." Dallas brought the 25-year-old over from Memphis in July after he averaged 14.0 points, 6.7 rebounds, and 1.6 three-pointers last season. Once healthy, his ability to stretch the floor should keep him firmly in the frontcourt rotation.

Philadelphia's G Tyrese Maxey scored 32 points on 12-of-23 shooting in a 114-106 win over the Cavaliers on Thursday, Oct. 22. Maxey is owned in only 61.1% leagues.

San Antonio Spurs forward Tobias Harris (calf) will miss his second consecutive game Friday against the Houston Rockets. Harris continues to recover from a left calf strain and has yet to make his Spurs debut. The 34-year-old veteran averaged 13.3 points, 5.1 rebounds, and 2.5 assists across 63 starts for Detroit last season before signing a two-year, $31 million deal with San Antonio. His next opportunity to suit up comes Saturday against the Dallas Mavericks. Julian Champagnie and Devin Vassell remain appealing streaming options while Harris is sidelined.

Los Angeles Lakers forward Jake LaRavia (ankle) is listed as questionable for Friday's matchup against the Los Angeles Clippers. LaRavia sprained his right ankle during Wednesday's win over the Warriors, finishing with 10 points, two assists, two rebounds, and one steal in 18 minutes before exiting. If the 24-year-old is unable to suit up Friday, Quentin Grimes, Matisse Thybulle, and Ziaire Williams could see additional playing time, potentially boosting their short-term fantasy value.

Sacramento Kings guard Malik Monk (ankle) is listed as probable for Friday's matchup against the Los Angeles Clippers. Monk has been dealing with left ankle soreness throughout training camp and missed Wednesday's regular-season opener. He averaged 12.5 points, 3.0 assists, and 2.0 three-pointers across 62 games last campaign. With Ben Simmons (Achilles) out for the season, Sacramento's backcourt depth is already being tested, so Monk's return could be a big boost. If he stays healthy, the 28-year-old could provide solid fantasy value with his scoring and three-point shooting.

Los Angeles Lakers guard Collin Sexton (calf) is available for Friday's matchup against the Los Angeles Clippers. The 27-year-old missed Wednesday's regular-season opener due to a calf strain but is now set to make his Lakers debut. Sexton averaged 17.5 points, 2.9 rebounds, 2.5 assists, and 1.5 steals in 26 games with Chicago last season while shooting 48.2 percent from the field and 41.0 percent from three-point range. His fantasy upside could be limited in 2026-27, as Luka Doncic and Austin Reaves are expected to handle most of the Lakers' offensive responsibilities.

Golden State Warriors guard Brandin Podziemski (back) is listed as questionable for Friday's matchup against the Memphis Grizzlies. Podziemski missed Wednesday's regular-season opener, a 127-105 loss to the Lakers due to bilateral lower-back soreness and could miss his second straight contest. The 23-year-old averaged a career-high 13.8 points in 28.5 minutes per game during the 2025-26 campaign and should remain a useful fantasy contributor once healthy.

According to Justin Martinez of The Oklahoman, Denver Nuggets forward Spencer Jones (hamstring) will miss Thursday's regular-season opener against the Oklahoma City Thunder. Jones strained his left hamstring early in training camp and is now also dealing with a right hamstring injury. Trevor Brazile could see additional minutes in Jones' absence, but he is unlikely to make a significant fantasy impact Thursday.

Orlando Magic guard/forward Anthony Black (ankle) was a full participant in Thursday's practice, according to head coach Sean Sweeney. The session was mostly a walkthrough and film work following Wednesday's loss to Atlanta, but Black also got shots up afterward. The 22-year-old missed the entire preseason and the opener with a right ankle sprain, making Friday's matchup with Minnesota his next chance to return. Black averaged 15.0 points, 3.7 assists, and 1.4 steals in 29.8 minutes last season. His return would tighten Orlando's bench rotation after Tristan da Silva scored 14 points with four threes Wednesday.

Memphis Grizzlies guard Ty Jerome poured in a career-high 45 points in Wednesday's 123-103 win over the Utah Jazz, adding seven rebounds, six assists, and five three-pointers. He shot 17-for-25 from the field and committed just one turnover in 32 minutes, breaking Ja Morant's franchise opening-night record of 44 points. With Morant now in Portland, Jerome has the keys to Memphis' offense, and Wednesday was a strong first look at what that role can produce. The bigger question is durability after injuries limited the 29-year-old to 15 games last season, but the opportunity is there for a major jump if he can stay on the floor.

Phoenix Suns center Oso Ighodaro (hip) exited Wednesday's 124-83 loss to the Portland Trail Blazers shortly before halftime and did not return. The 24-year-old was seen grabbing at his right hip after missing the preseason finale with hip soreness. Ighodaro had eight points, three rebounds, and three assists on 4-for-7 shooting in 14 minutes before leaving. With Mark Williams (shoulder) sidelined for an extended period, any absence would leave Khaman Maluach with a larger role at center and could push two-way big Duop Reath into the rotation. Maluach saw only 8.9 minutes per game as a rookie, but there would be plenty more opportunity available if Ighodaro is forced to miss time.

Cleveland Cavaliers center Jarrett Allen (knee) said he expects to play in Thursday's season opener against the Philadelphia 76ers, according to Chris Fedor. Allen remains questionable with right patellar tendinopathy, the same knee that cost him 10 games last March. The 28-year-old averaged 15.4 points, 8.5 rebounds, 1.8 assists, and 1.0 steal on 63.8 percent shooting across 56 games last season. His optimism puts him on track for his usual starting role, though fantasy managers should still confirm his status before tip-off. If Allen is ruled out, Evan Mobley would likely shift to center, with Jaylon Tyson a candidate to enter the starting five.

Washington Wizards forward AJ Dybantsa (ankle) is out for Friday's game against the Toronto Raptors, according to head coach Brian Keefe. The 19-year-old remains day-to-day with the left ankle sprain he suffered in the preseason finale, delaying his NBA debut for a second straight game. Dybantsa averaged 12.8 points in 21.5 minutes across four preseason appearances. Bilal Coulibaly started in his place Wednesday and delivered 11 points, four steals, and two blocks on 4-for-6 shooting. With Dybantsa sidelined again, Coulibaly should remain heavily involved, and his ability to pile up defensive stats gives him some short-term fantasy appeal.

Philadelphia 76ers center Tacko Fall (quadriceps) is out for Thursday's home opener against the Cleveland Cavaliers. The 30-year-old missed the entire preseason with a separate left hip strain before landing a two-way deal Saturday, and he also sat out Tuesday's win over New York. Fall hasn't appeared in an NBA game since 2021-22, so his absence carries little fantasy weight. Adem Bona should continue handling the backup center minutes behind Joel Embiid after recording three rebounds, one assist, and one block in 10 minutes Tuesday. With Dominick Barlow (back) and Ariel Hukporti (Achilles) also out and Dean Wade (ankle) questionable, Philadelphia could turn to more small-ball looks with LeBron James.

Los Angeles Clippers guard Bradley Beal (knee) won't play this week or travel for Sunday's game against the Oklahoma City Thunder, according to Joey Linn. The 33-year-old continues to manage right knee inflammation after recovering from surgery for last season's left hip fracture, and there remains no firm timetable for his return. His absence should keep rookie Keaton Wagler involved after he posted 15 points, five rebounds, and five assists in Wednesday's opener, while Darius Garland handled much of the scoring with 30 points. Beal had yet to resume five-on-five work earlier this month, so there is still little reason to expect a quick return.

Los Angeles Clippers guard/forward Brandon Ingram (Achilles) will remain sidelined this week and will not travel for Sunday's road game against the Oklahoma City Thunder. The two-time All-Star is making progress after undergoing surgery on his right heel in May that also addressed a partially torn Achilles tendon, but there is still no timetable for his return. Ingram averaged 21.5 points, 5.6 rebounds, and 3.7 assists across 77 games for Toronto last season. Rui Hachimura should continue starting in his absence, while rookie Keaton Wagler has a path to steady bench usage after posting 15 points, five rebounds, and five assists in Wednesday's opener.