The Kansas City Royals have placed starting pitcher Cole Ragans (groin) on the 15-day injured list with a left groin strain. Ragans exited his start on Friday due to groin tightness and will now be held out of action for at least the next two weeks. The 27-year-old has enjoyed a strong start to the season, holding a 4.53 ERA with a 1.20 WHIP across 45 2/3 innings. Ragans has tallied an impressive 72 strikeouts, which is the second-highest total in the American League. Under the hood, Ragans has generated a 2.29 xERA and a .190 xBA, which place him in the 95th and 93rd percentile, respectively. Earlier on Saturday, the Royals also placed Seth Lugo (finger) on the 15-day IL. While Noah Cameron is set to replace Lugo, the team has yet to announce who will replace Ragans in the rotation. Fantasy managers should stash Ragans in all formats, given his elite strikeout potential.

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The Kansas City Royals have placed starting pitcher Seth Lugo (finger) on the 15-day injured list due to a finger sprain. Lugo was initially expected to get the starting nod on Saturday, but saw his start pushed back. However, Lugo will now be held out of action for at least the next two weeks. Fantasy managers should continue to monitor his status while he is sidelined. This afternoon, the Royals promoted Noah Cameron from Triple-A to take his spot in the rotation. If he performs well, Cameron should be the favorite to remain in the rotation for the next two weeks. Through 56 2/3 innings this season, the 35-year-old has posted a strong 3.02 ERA with a 1.09 WHIP. While he has only struck out 42 batters, he has provided excellent ratios. Fantasy managers in standard formats should stash Lugo while he is sidelined.

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Baltimore Orioles outfielder Colton Cowser (thumb) was able to take live batting practice on Saturday. Cowser has been sidelined since late March due to a fractured left thumb. However, seeing him increase his baseball activities is a positive sign. If Cowser continues to progress well, he could be cleared to embark on a rehab assignment in the coming weeks. Last summer, the 25-year-old appeared in a career-high 135 games with the Orioles. Across this stint, he held a .242/.321/.447 slash line with 24 doubles, 24 home runs, and nine stolen bases. When Cowser returns to action, he should have an everyday role in left field. While he remains out, fantasy managers should expect Ramon Laureano, Heston Kjerstad, and Tyler O'Neill to see most of the opportunities in left field.

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Baltimore Orioles first baseman Ryan Mountcastle is not in Saturday's lineup when the Orioles continue a series against the Washington Nationals. Mountcastle has started in each of the past 18 games. Fantasy managers should expect the 28-year-old to return to the starting nine on Sunday. Over his last 18 contests, Mountcastle has posted a .239/.263/.366 slash line with six doubles, one home run, and nine RBI. During this stretch, he has held an 18:3 K:BB. Under the hood, Mountcastle has generated an above-average .264 xBA and a .456 xSLG, which suggest he should continue to see positive regression later this season. He has also generated an elite 50.9% hard-hit rate. This afternoon, Ryan O'Hearn will shift to first base and will bat in the two-hole.

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Baltimore Orioles outfielder Tyler O'Neill (shoulder) remains out of the starting lineup on Saturday when they continue a series against the Washington Nationals. O'Neill was scratched from the lineup on Friday due to discomfort in his left shoulder. Fantasy managers should continue to monitor his status leading up to Sunday's game, in case the Orioles continue to hold him out of action. Over his last seven games, O'Neill has tallied just one hit and swiped two bags. This afternoon, Heston Kjerstad will cover right field, which opens left field for Ramon Laureano. Through 24 games this season, O'Neill has held a modest .188 AVG with a hefty 29% strikeout rate. The Orioles are worth targeting in DFS facing Washington right-hander Jake Irvin.

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Miami Marlins catcher Agustin Ramirez and outfielder Derek Hill are not in the starting lineup on Saturday when they continue a series against the Tampa Bay Rays. Since being promoted to the major leagues, Ramirez has taken the starting job behind the dish. Over his last 10 games, Ramirez has been productive at the plate, holding a .297/.381/.596 slash line with five doubles and two home runs. In addition, outfielder Derek Hill will take a seat. Hill has started in each of the past four games since returning from the injured list. Over his last four, Hill has held a .214 AVG with two RBI. As a result, Nick Fortes will be behind the dish and Liam Hicks will serve as the DH. The Marlins are best to fade in DFS this afternoon, facing Tampa right-hander Drew Rasmussen.

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Detroit Tigers shortstop Trey Sweeney is not in Saturday's lineup when they continue a series against the Toronto Blue Jays. Sweeney has been in the starting nine in each of the past four games. During this stretch, Sweeney has held a strong .294 AVG with a home run and six RBI. Over his last 14 contests, Sweeny has been one of the most productive hitters in the sport, as he posted an impressive .357/.362/.536 slash line with one double, three home runs, and 13 RBI. This afternoon, Zach McKinstry will get the starting nod at shortstop and will bat in the nine-hole. Fantasy managers should expect Sweeney to return to the lineup on Sunday. McKinstry and the Tigers are a viable target in DFS facing Toronto left-hander Eric Lauer, who has only served in a bulk relief role this season.

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Miami Marlins shortstop Xavier Edwards (back) remains out of the starting lineup on Saturday when they continue a series against the Tampa Bay Rays. Edwards was held out of action on Friday due to lower back tightness. Fantasy managers should continue to monitor his status leading up to Sunday's game, in case he needs additional time off. With Edwards sitting out, Javier Sanoja will get the starting nod at shortstop and bat in the nine-hole. Through his first 42 games of the season, Edwards has posted a .263/.337/.292 slash line with 11 stolen bases. He has drawn walks at a 9.8% rate and struck out at a 17.5% rate, which are both above the average marks. Given his elite speed upside, he should remain stashed in all category formats while he is sidelined.

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Tampa Bay Rays third baseman Junior Caminero is not in Saturday's lineup when they continue a series against the Miami Marlins. Caminero has been in the starting nine in each of the past 10 games. Over this stretch, the former top prospect has posted a .243/.268/.405 slash line with two home runs and seven RBI. Instead, Jose Caballero will get the nod at the hot corner and is set to bat in the six-hole. Fantasy managers should expect Caminero to return to the lineup on Sunday. Through 42 games this season, Caminero has posted a .241/.272/.426 slash line with eight home runs and two stolen bases. He has generated an elite 50.8% hard-hit rate with a .460 xSLG, which suggests he should see positive regression. The Rays are a viable target in DFS facing Sandy Alcantara, who enters this game holding an 8.10 ERA.

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Arizona Diamondbacks catching prospect Adrian Del Castillo (shoulder) recently began his throwing program. Fantasy managers should continue to monitor his status as he could be cleared to begin a rehab assignment in the coming weeks. The backstop is currently considered the No. 6 prospect in the Arizona system. Del Castillo made his MLB debut last season and performed quite well, posting a .313/.368/.526 slash line across 25 games. He went deep four times, added five doubles, and tallied 19 RBI. Before reaching the majors, Del Castillo spent his 2024 season with the Reno Aces, where he performed at an elite level, posting a .312/.399/.603 slash line across 105 games. When Del Castillo is cleared to return to action, he should push for an early return to the big leagues.

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Chicago White Sox left-handed pitcher Tyler Gilbert (knee) was placed on the 15-day injured list due to a sprained MCL in his left knee. In a corresponding move, the White Sox have promoted left-handed pitcher Jared Shuster from Triple-A Charlotte. Through 13 games this season, Gilbert has been deployed both as an opener and out of the bullpen. In 13 innings of work, the southpaw has struck out 16 batters and posted a 4.85 ERA with a 1.15 WHIP. However, under the hood, Gilbert has generated an impressive 3.62 xERA and a strong .206 xBA, which are both well above the average marks. While Gilbert remains sidelined, fantasy managers should expect Shuster to serve in a similar middle-relief role in the bullpen. Fantasy managers should continue to expect Jordan Leasure and Cam Booser to see most of the high-leverage opportunities.

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Toronto Blue Jays outfielder Anthony Santander (hip) remains out of the starting nine on Saturday when the Blue Jays continue a series against the Detroit Tigers. Arden Zwelling noted that the slugger is dealing with a sore left hip. On Friday, Santander was dealing with a sore left shoulder. Fantasy managers should continue to monitor his status leading up to Sunday's contest. As a result, this will open the DH spot for first baseman Vladimir Guerrero Jr., which opens first base for Ernie Clement. Through his first 39 games of the campaign, Santander has held a modest .187/.266/.316 slash line with just five doubles and five home runs. Under the hood, he has generated a low .283 xwOBA. The Blue Jays are worth considering in DFS facing Reese Olson, who enters this game with a 3.38 ERA.

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Cincinnati Reds outfielder Austin Hays continued to produce in the team's 5-4 win over the visiting Cleveland Guardians at Great American Ball Park on Friday night, going 2-for-4 with his sixth home run of the season and his second stolen base of 2025. Hays' home run in the third inning of the ballgame opened the Reds' lead up to five runs, and it was his first long ball since he came off the injured list last week. The 29-year-old former third-round pick by the Baltimore Orioles in 2016 out of Jacksonville University has produced for Cincy as their regular left fielder when healthy this year, going 24-for-76 (.316) with six homers, 16 RBI, 16 runs scored and two steals. Since returning from the IL on May 9, Hays has gone 5-for-24 (.208) with a homer, double, three RBI, one steal and one run scored while striking out nine times in 25 plate appearances.

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Washington Nationals outfielder James Wood stayed hot at the plate in Friday's 4-3 win over the Baltimore Orioles at Camden Yards, going 2-for-4 with a single, his 12th home run of the season, two RBI, and two strikeouts as the designated hitter out of the three-hole. Wood has been very productive for his fantasy managers in his first full season in the big leagues, hitting .273/.366/.540 with a .906 OPS, 12 homers, 11 doubles, 27 RBI, 25 runs scored and five stolen bases in 46 games played. The 22-year-old's home run in the eighth inning was a big one, as it tied the score up at three apiece in the eventual win. Wood now has 11 multi-hit games on the year and has improved in the month of May, hitting .317/.379/.533 with three home runs, six RBI and two steals in 66 plate appearances. He's a must-start in fantasy.

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The New York Mets announced on Saturday that they reinstated infield prospect Ronny Mauricio (knee) from the 10-day injured list and optioned him to Triple-A Syracuse. Mauricio's rehab assignment has ended, but he's going to need more time in the minors after missing all of last season while recovering from multiple surgeries for a torn ACL. The 24-year-old is considered the team's No. 9 prospect, per MLB Pipeline, but he probably won't be a realistic option to return to the big leagues until some point in the second half of this season. He went 4-for-32 during his rehab assignment and hit .248 (25-for-101) with two homers, nine RBI, seven steals and 11 runs scored in 26 games during his MLB debut back in 2023. Mauricio has intriguing power upside but needs to clean up his plate discipline to succeed at the next level. He's strictly a stash option in dynasty/keeper leagues at the moment.

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Seattle Mariners right-hander George Kirby (shoulder) made his third minor-league rehab start with Triple-A Tacoma on Friday night and allowed four earned runs on 10 hits (two home runs) while walking none and striking out four in four innings pitched. While the results weren't all that great for Kirby in this one, the primary takeaway is that he didn't suffer any setbacks with his shoulder and hit 97.5 mph with his four-seam fastball. The 27-year-old hasn't been a big strikeout guy to this point of his career, but he's useful in fantasy for his pinpoint control, and he has yet to walk any of the 21 batters he's faced so far on his rehab assignment. Kirby is getting closer to making his 2025 season debut, but he only threw 64 pitches on Friday night, so it would make sense for the M's to give him one more rehab start. If Kirby is available on your league's waiver wire, pick him up now.

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Los Angeles Angels third baseman Yoan Moncada (thumb) left the 6-2 win over the Los Angeles Dodgers on Friday night early after he seemed to aggravate his thumb injury on a swing in the top of the ninth inning, according to the Orange County Register's Jeff Fletcher. Manager Ron Washington said it's something that is going to happen whenever he swings and misses in a certain way (usually at breaking balls). Moncada went 1-for-5 with his third home run of the season, two RBI and two strikeouts in the contest before leaving late and being replaced by Kevin Newman. The 29-year-old oft-injured infielder missed almost a month earlier this year with a right-thumb sprain, so he could be headed back to the injured list. If he were to miss extended time again, the Angels could use Newman and Tim Anderson at the hot corner.

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Atlanta Braves outfielder Ronald Acuna Jr. appeared in his second minor-league rehab game with Triple-A Gwinnett on Friday night and went 0-for-2 at the plate with two walks and two runs scored while playing right field and hitting leadoff for the Stripers. Acuna homered in his first rehab game in the rookie-level Florida Complex League and had two hits (one double) in his first contest with Gwinnett on Thursday. The 27-year-old played six innings in right field on Friday as he recovers from a torn left ACL last year. The Braves still have no official timetable for Acuna's return to the big leagues, but they aren't going to rush him back until he's ready to play full games in right field on a daily basis, so it could be at least another week or two. Fantasy managers need to remain patient on the former MVP, but he could once again be a difference-maker when he makes his 2025 debut.

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Texas Rangers third baseman Josh Jung went 2-for-4 with a solo home run and tworuns scored in Friday's 6-3 loss to the Astros. He was the only Ranger to get multiple hits in the game and has recordedmultiple hits in four of his last six games. The former first-round draft pick is hitting .291 on the year, with 18 RBI and 15 runs scored in 37 games played. With a .361 wOBA and 135 wRC+, the right-handed hitter has been productive, so hopefully he can remain healthy for the remainder of the campaign after being limitedto only 46 games in 2024 and missing time on the IL once already earlier thisyear. The 27-year-old has career bests in contact rate, strikeout rate, and barrel rate thus far, and he'll take on the Astros' Ronel Blanco on Saturday, whom he is 3-for-3 off of in his career, with a walk, a double, and a home run.

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Pittsburgh Pirates outfielder Alexander Canario went 2-for-3 with a walk and a three-run home run in Friday's 8-4 loss to the Phillies. The 25-year-old is now riding a seven-game hit streak, with the last three going down as multi-hit efforts. Without any minor leagueoptions remaining, the Pirates are giving Canario a shot at regular at-bats after acquiring him from the Mets in exchangefor cash earlier this season. It got off to a rough start, going 2-for-27 (.074) over his first 12 games withthe club, but over the last 11 games, the Dominican is 13-for-38 (.342) with two doubles, two home runs, five RBI, and five runs scored. The 6-foot-1 slugger has big-time power, as evidenced by a 37-homer campaign in the minors back in 2022, but had struggled mightily with strikeouts in the majors prior to this season, registeringa 42.2 percent K% headinginto 2025. He's lowered that to 25.0 percent this year, which could make him an intriguing waiver option if he keeps hitting.

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